TOP IS FENTANYL CONSIDERED A CHEAP DRUG SECRETS

Fentanyl binds to opioid receptors, Particularly the mu opioid receptor, which might be coupled to G-proteins.six Activation of opioid receptors leads to GTP being exchanged for GDP over the G-proteins which in turn down regulates adenylate cyclase, lowering concentrations of cAMP.Fentanyl is really a synthetic opioid that was at first developed as